Herceptin plus arimidex extends lives of breast cancer patients

Herceptin plus arimidex extends lives of breast cancer patients

Herceptin combined with Arimidex extends the lives of patients with advanced HER2-positive breast cancer, says Swiss pharmaceutical company, Roche. The company announced that the combination had a significant impact on patients' progressions-free survival.

Patients with HER2-positive breast cancer suffer from an especially fast-progressing cancer. This cancer is a hormone receptive positive cancer and prognosis is usually bad. About 25% of all hormone receptor-positive cancers are of the HER2-positive type. Breast cancers of the hormone receptor-positive type represent over 60% of all breast cancers.

Most hormone receptor-positive breast cancers are considered low-risk and are usually successfully treated with hormonal therapies. However, HER2-positive type breast cancer is an exception - it is aggressive and has a higher probability of relapse.

Herceptin is currently approved just for metastatic cancer in Europe. Metastatic cancer means the tumors have spread around the body. Experts in Europe are in favour of the earlier use of the drug - meaning it would be used by many more women, especially younger ones.

Roche said the Phase III trial results indicated benefits for both HER2-positive patients as well as those with other hormone receptor-positive cancers.

The study compared Herceptin with Arimidex to Arimidex alone for women with HER2-positive and hormone receptor-positive breast cancer.

Herceptin is injected into the patient. It has been shown to be particularly effective with patients whose tumour generates a protein called HER2. HER2 accelerates the speed at which the tumour grows.

Herceptin is marketed worldwide by Roche, except for Japan where it is marketed by Chugai, and the USA where it is marketed by Genentech.

Editor: Medical-Diag.com

About Her2 Positive Breast Cancer Drug Perjeta ( Pertuzumab ) (Video Medical And Professional 2020).

Section Issues On Medicine: Women health